MagicSeb of gx-mod.com released a new port for homebrew 360s. REminiscene 360 is a port of REminiscence, a rewrite of the engine used in the game Flashback from Delphine Software. This program is designed as a cross-platform replacement for the original executable and uses the SDL library.
You'll need the data- and music-files from the original PC game to use this interpreter and place them in the DATA folder.